FOXA1, forkhead box A1, 3169

N. diseases: 138; N. variants: 1
Disease: Prostatic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.330 AlteredExpression group BEFREE Partitioning the genome according to cistromes reveals the enrichment of somatic SNVs in prostate tumors as opposed to adjacent normal tissue cistromes of master transcription regulators, including AR, FOXA1, and HOXB13. 31735626 2019
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.330 Biomarker group CTD_human Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations. 29295717 2018
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.330 Biomarker group CTD_human The long tail of oncogenic drivers in prostate cancer. 29610475 2018
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.330 Biomarker group CTD_human Introduction of FOXA1 and HOXB13 into an immortalized prostate cell line reprogrammed the AR cistrome to resemble that of a prostate tumor, functionally linking these specific factors to AR cistrome reprogramming. 26457646 2015
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.330 Biomarker group BEFREE Using orthotopic mouse models, we further show that FoxA1 inhibits prostate tumor metastasis in vivo. 23539448 2013
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.330 Biomarker group CTD_human Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. 22610119 2012
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.330 Biomarker group LHGDN Hepatocyte nuclear factor-3 alpha (HNF-3alpha) negatively regulates androgen receptor transactivation in prostate cancer cells. 18178153 2008