HP, haptoglobin, 3240

N. diseases: 464; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002871
Disease: Anemia
Anemia
0.380 Biomarker disease BEFREE Patients with anemia or abnormal hemolysis markers (LDH, haptoglobin) were included in the analysis. 30280481 2019
CUI: C0002871
Disease: Anemia
Anemia
0.380 AlteredExpression disease BEFREE The aim of the study was to investigate zonulin levels in patients with early stages of CKD and its possible correlation with inflammation, anemia and iron status parameters. 29134616 2018
CUI: C0002871
Disease: Anemia
Anemia
0.380 Biomarker disease BEFREE Low plasma haptoglobin is a risk factor for life-threatening childhood severe malarial anemia and not an exclusive consequence of hemolysis. 30510258 2018
CUI: C0002871
Disease: Anemia
Anemia
0.380 Biomarker disease BEFREE Reasons for pnh testing were anemia (<i>n</i> = 3), new mds diagnosis (<i>n</i> = 2), hypoplastic mds (<i>n</i> = 2), decreased haptoglobin (<i>n</i>= 1), increased rbc transfusion requirement (<i>n</i>= 1), and unexplained iron deficiency (<i>n</i>= 1). 30464689 2018
CUI: C0002871
Disease: Anemia
Anemia
0.380 Biomarker disease BEFREE Laboratory tests on blood samples revealed acute renal failure, with a creatinine level of 3.98 mg/dL, thrombocytopenia of 47 × 10<sup>9</sup>/L, lactate dehydrogenase level of 3620 IU/L, low haptoglobin (<20 mg/dL), anemia (10.0 g/dL) and schistocytes on blood smears. 28780656 2017
CUI: C0002871
Disease: Anemia
Anemia
0.380 Biomarker disease BEFREE Day 5 post-delivery, she developed HELLP, with hemolytic anaemia (Hb 10.1 g/dL, haptoglobin <30 g/L, LDH 2206 U/L), elevated transaminases (AST 1196 U/L, ALT 1130 U/L) and thrombocytopenia (platelet 28 × 10^9/L). 27694537 2017
CUI: C0002871
Disease: Anemia
Anemia
0.380 GeneticVariation disease BEFREE To retest our previous finding that the haptoglobin (Hp) 22 genotype is associated with seasonal anaemia, and to investigate the role of malaria in this effect. 18291005 2008
CUI: C0002871
Disease: Anemia
Anemia
0.380 Biomarker disease CTD_human Previous studies examined the importance of haptoglobin polymorphism in malaria and iron homeostasis, but it is unknown whether haptoglobin genotype might be a risk factor for anaemia in children in a malaria-endemic area. 16637741 2006
CUI: C0002871
Disease: Anemia
Anemia
0.380 GeneticVariation disease BEFREE Previous studies examined the importance of haptoglobin polymorphism in malaria and iron homeostasis, but it is unknown whether haptoglobin genotype might be a risk factor for anaemia in children in a malaria-endemic area. 16637741 2006