HP, haptoglobin, 3240

N. diseases: 464; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011875
Disease: Diabetic Angiopathies
Diabetic Angiopathies
0.340 GeneticVariation disease BEFREE Over the past decade, several longitudinal epidemiological studies have brought attention to the haptoglobin genotype and its importance in determining diabetic vascular disease risk. 22447230 2012
CUI: C0011875
Disease: Diabetic Angiopathies
Diabetic Angiopathies
0.340 Biomarker disease CTD_human Iron and infection: effects of host iron status and the iron-regulatory genes haptoglobin and NRAMP1 (SLC11A1) on host-pathogen interactions in tuberculosis and HIV. 16597321 2006
CUI: C0011875
Disease: Diabetic Angiopathies
Diabetic Angiopathies
0.340 Biomarker disease BEFREE These Hp-modified mice may serve as a platform on which to test a variety of pharmacological agents in order to decrease diabetic vascular disease. 15852445 2005
CUI: C0011875
Disease: Diabetic Angiopathies
Diabetic Angiopathies
0.340 GeneticVariation disease BEFREE We recently demonstrated that a functional allelic polymorphism in the haptoglobin gene is correlated with a number of diabetic vascular complications. 11888529 2002
CUI: C0011875
Disease: Diabetic Angiopathies
Diabetic Angiopathies
0.340 Biomarker disease BEFREE Identification of the biochemical basis for differences among haptoglobin types may lead to the rational development of new pharmacologic agents, such as the mini-haptoglobin described here, to avert the development of diabetic vascular complications. 11739174 2001