BIRC5, baculoviral IAP repeat containing 5, 332

N. diseases: 199; N. variants: 11
Disease: Malignant neoplasm of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.340 Biomarker disease BEFREE The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5. 31508486 2019
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.340 AlteredExpression disease BEFREE Finally, bioinformatics analyses directed to identify which gene combinations had synergistic effects on clinical outcome in lung cancer showed that poor survival is associated with high co-expression of SCD1, β-catenin and the YAP/TAZ downstream target birc5. 28368399 2017
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.340 Biomarker disease BEFREE Our findings defined a 3' UTR SNP in human BIRC5 oncogene that may increase individual susceptibility to lung cancer probably by attenuating the interaction between miR-335 and BIRC5. 23232114 2013
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.340 AlteredExpression disease BEFREE BIRC5 mRNA was also significantly different between patients with Stage III and Stage IV non-small cell lung cancers. 19585499 2009
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.340 Therapeutic disease CTD_human Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin. 16108013 2006
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.340 Biomarker disease CTD_human Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin. 16108013 2006
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.340 Therapeutic disease CTD_human Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation. 15981204 2005
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.340 Biomarker disease CTD_human Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation. 15981204 2005