BIRC5, baculoviral IAP repeat containing 5, 332

N. diseases: 199; N. variants: 11
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker disease BEFREE The hub gene BIRC5, which might play a key role in ovarian neoplasms, was further screened. 31177266 2019
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker disease BEFREE An increasing number of studies have confirmed that survivin (BIRC5) plays essential roles in ovarian cancer. 29499854 2018
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker disease BEFREE Hedgehog signaling pathway has been implicated in the pathology of ovarian cancer, and Survivin (BIRC5) has been suggested as a novel target of this pathway. 29039491 2017
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 AlteredExpression disease BEFREE Collectively, our studies demonstrated that disruption of BIRC5 expression inhibited EMT by attenuating the TGFβ pathway in ovarian cancer cells. 29212257 2017
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 AlteredExpression disease LHGDN Implication of the Akt2/survivin pathway as a critical target in paclitaxel treatment in human ovarian cancer cells. 18842333 2009
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Therapeutic disease CTD_human Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients. 18567002 2008
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 AlteredExpression disease LHGDN NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomas. 18593915 2008
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker disease CTD_human Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients. 18567002 2008
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 AlteredExpression disease LHGDN The prognostic significance of COX-2 and survivin expression in ovarian cancer. 18171606 2008
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Therapeutic disease CTD_human [Influence of short hairpin RNA on survivin mRNA expression and chemosensitivity to paclitaxel in ovarian cancer cells]. 16202317 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker disease CTD_human Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death. 16211241 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Therapeutic disease CTD_human Changes in survivin messenger RNA level during chemotherapy treatment in ovarian cancer cells. 15970709 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Therapeutic disease CTD_human Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death. 16211241 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker disease CTD_human [Influence of short hairpin RNA on survivin mRNA expression and chemosensitivity to paclitaxel in ovarian cancer cells]. 16202317 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker disease CTD_human Changes in survivin messenger RNA level during chemotherapy treatment in ovarian cancer cells. 15970709 2005