BIRC5, baculoviral IAP repeat containing 5, 332

N. diseases: 199; N. variants: 11
Disease: Malignant neoplasm of ovary ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Biomarker disease BEFREE An increasing number of studies have confirmed that survivin (BIRC5) plays essential roles in ovarian cancer. 29499854 2018
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 AlteredExpression disease BEFREE Collectively, our studies demonstrated that disruption of BIRC5 expression inhibited EMT by attenuating the TGFβ pathway in ovarian cancer cells. 29212257 2017
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Biomarker disease BEFREE Hedgehog signaling pathway has been implicated in the pathology of ovarian cancer, and Survivin (BIRC5) has been suggested as a novel target of this pathway. 29039491 2017
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Biomarker disease CTD_human Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients. 18567002 2008
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Therapeutic disease CTD_human Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients. 18567002 2008
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Biomarker disease CTD_human Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death. 16211241 2005
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Therapeutic disease CTD_human Changes in survivin messenger RNA level during chemotherapy treatment in ovarian cancer cells. 15970709 2005
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Therapeutic disease CTD_human Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death. 16211241 2005
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Biomarker disease CTD_human [Influence of short hairpin RNA on survivin mRNA expression and chemosensitivity to paclitaxel in ovarian cancer cells]. 16202317 2005
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Biomarker disease CTD_human Changes in survivin messenger RNA level during chemotherapy treatment in ovarian cancer cells. 15970709 2005
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.330 Therapeutic disease CTD_human [Influence of short hairpin RNA on survivin mRNA expression and chemosensitivity to paclitaxel in ovarian cancer cells]. 16202317 2005