Liver carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, we deeply mined the integrated large-scale datasets from public microarrays and immunohistochemistry to validate the overexpression of BIRC5 and SQSTM1 while down-regulated FOXO1 expression in HCC.
|
29707114 |
2018 |
Liver carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Besides, genes BIRC5, CDC20, CCNB1, BUB1B, MAD2L1 and CDK1 as the hub genes might play important roles for diagnosing and therapy of HCC.
|
25753876 |
2015 |
Liver carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Additionally, plasmid-based siRNA against Birc5 and/or Hspa5 were constructed and transfected into the human hepatocellular liver carcinoma cell line, HepG2.
|
22581315 |
2012 |
Liver carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Compared the same and different activated and inhibited BIRC5 network with GO analysis between no-tumor hepatitis/cirrhosis and HCC, our result showed BIRC5 cell cycle network weaker transcription factor activity in both no-tumor hepatitis/cirrhosis and HCC (1); stronger nucleus protein binding but weaker cytoplasm protein binding in no-tumor hepatitis/cirrhosis (2); stronger cytoplasm protein phosphatase binding but weaker ubiquitin-protein ligase activity in HCC (3).
|
21312234 |
2011 |
Liver carcinoma
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Resistance to cisplatin-induced apoptosis via PI3K-dependent survivin expression in a rat hepatoma cell line.
|
20514400 |
2010 |
Liver carcinoma
|
0.400 |
Biomarker
|
disease |
CTD_human |
Resistance to cisplatin-induced apoptosis via PI3K-dependent survivin expression in a rat hepatoma cell line.
|
20514400 |
2010 |
Liver carcinoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
[Down-regulation of survivin in growth inhibition of hepatoma cells induced by a selective cyclooxygenase-2 inhibitor].
|
18815458 |
2008 |
Liver carcinoma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Relationship between survivin expression and recurrence, and prognosis in hepatocellular carcinoma.
|
18069771 |
2007 |
Liver carcinoma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Survivin expression in early hepatocellular carcinoma and post-treatment with anti-cancer drug under hypoxic culture condition.
|
17879398 |
2007 |
Liver carcinoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.
|
17087938 |
2006 |
Liver carcinoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Targeting of X-linked inhibitor of apoptosis protein or survivin by short interfering RNAs sensitize hepatoma cells to TNF-related apoptosis-inducing ligand- and chemotherapeutic agent-induced cell death.
|
16211302 |
2005 |
Liver carcinoma
|
0.400 |
Biomarker
|
disease |
CTD_human |
[Effect of inhibiting survivin expression with antisense oligodeoxynucleotides on sensitivity of hepatocellular carcinoma cell lines HepG2 and HepG2/ADM to adriamycin].
|
16086872 |
2005 |
Liver carcinoma
|
0.400 |
Therapeutic
|
disease |
CTD_human |
[Effect of inhibiting survivin expression with antisense oligodeoxynucleotides on sensitivity of hepatocellular carcinoma cell lines HepG2 and HepG2/ADM to adriamycin].
|
16086872 |
2005 |
Liver carcinoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Expression and significance of new inhibitor of apoptosis protein survivin in hepatocellular carcinoma.
|
15991282 |
2005 |
Liver carcinoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Hepatitis B virus X protein upregulates survivin expression in hepatoma tissues.
|
16173017 |
2005 |
Liver carcinoma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Survivin expression in hepatocellular carcinoma: correlation with proliferation, prognostic parameters, and outcome.
|
15195112 |
2004 |
Liver carcinoma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Expression of survivin mRNA associates with apoptosis, proliferation and histologically aggressive features in hepatocellular carcinoma.
|
15547736 |
2004 |
Liver carcinoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
The effect of ursodeoxycholic acid on the survivin in thapsigargin-induced apoptosis.
|
12609713 |
2003 |
Liver carcinoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Inducible nitric oxide synthase and survivin messenger RNA expression in hepatocellular carcinoma.
|
12374680 |
2002 |