HTR1A, 5-hydroxytryptamine receptor 1A, 3350

N. diseases: 229; N. variants: 9
Disease: Depression, Bipolar ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.320 Biomarker disease PSYGENET This is the first study that associated 5-HT1A receptor promoter gene variants with stressors preceding the need of hospitalization for bipolar depression. 21397953 2011
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.320 GeneticVariation disease BEFREE This is the first study that associated 5-HT1A receptor promoter gene variants with stressors preceding the need of hospitalization for bipolar depression. 21397953 2011
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.320 Biomarker disease PSYGENET Little is known about the serotonin-1A receptor (5-HT1A) in bipolar depression despite altered 5-HT1A binding in major depressive disorder. 19278673 2009
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.320 Biomarker disease BEFREE Brain 5-HT1A binding potential (BP(F) = B(max)/K(D), where B(max) = total available receptors, and 1/K(D) = ligand affinity) was measured in 32 currently depressed, medication-free BD subjects and 47 controls. 19278673 2009