Major depression, single episode
|
0.350 |
Biomarker
|
disease |
BEFREE |
We also found 14% higher 5-HT1A receptor binding (p = 0.045) and 21% lower SERT binding in BA 9 of individuals who had an MDE (p = 0.045).
|
31120232 |
2019 |
Major depression, single episode
|
0.350 |
Biomarker
|
disease |
PSYGENET |
Influence of the interaction between the serotonin 1A receptor C-1019G polymorphism and negative life stressors on the development of depression.
|
21577007 |
2011 |
Major depression, single episode
|
0.350 |
Biomarker
|
disease |
BEFREE |
Future studies should evaluate the role of genetic and environmental factors in producing elevated 5-HT(1A) BP(F) and MDD, and should examine whether 5-HT(1A) BP(F) is a vulnerability factor to MDEs that could have a role in screening high-risk populations for MDD.
|
19458612 |
2009 |
Major depression, single episode
|
0.350 |
Biomarker
|
disease |
PSYGENET |
Future studies should evaluate the role of genetic and environmental factors in producing elevated 5-HT(1A) BP(F) and MDD, and should examine whether 5-HT(1A) BP(F) is a vulnerability factor to MDEs that could have a role in screening high-risk populations for MDD.
|
19458612 |
2009 |
Major depression, single episode
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
In order to further delineate the impact of 5-HT1A gene variation on pharmacoresponse in depression over 6 weeks of antidepressant treatment, the influence of the 5-HT1A-1019C/G (rs6295) polymorphism was investigated in 340 Caucasian patients with a Major Depressive Episode (DSM-IV) with particular attention to the subtype of depression (major depression and melancholic depression).
|
18387740 |
2008 |
Major depression, single episode
|
0.350 |
Biomarker
|
disease |
PSYGENET |
Antidepressant treatment response across 5-HT1A-1019C/G genotype groups showed no differences in either Major Depressive Episode or major depression between genotype groups, whereas stratification for the melancholic subtype of depression revealed a significantly worse treatment response as conferred by the -1019CC genotype (p=0.02).
|
18387740 |
2008 |
Major depression, single episode
|
0.350 |
Biomarker
|
disease |
BEFREE |
Higher 5-HT1A receptor binding potential during a major depressive episode predicts poor treatment response: preliminary data from a naturalistic study.
|
16395308 |
2006 |
Major depression, single episode
|
0.350 |
Biomarker
|
disease |
PSYGENET |
Genotyped and determined 5-HT(1A) binding potential (BP) by positron emission tomography (PET) using [carbonyl-C-11]-WAY-100635 in 28 medication-free MDD subjects during a current major depressive episode and 43 controls.
|
16154547 |
2006 |
Major depression, single episode
|
0.350 |
Biomarker
|
disease |
BEFREE |
Genotyped and determined 5-HT(1A) binding potential (BP) by positron emission tomography (PET) using [carbonyl-C-11]-WAY-100635 in 28 medication-free MDD subjects during a current major depressive episode and 43 controls.
|
16154547 |
2006 |
Major depression, single episode
|
0.350 |
Biomarker
|
disease |
PSYGENET |
Higher 5-HT1A receptor binding potential during a major depressive episode predicts poor treatment response: preliminary data from a naturalistic study.
|
16395308 |
2006 |