IDE, insulin degrading enzyme, 3416

N. diseases: 71; N. variants: 19
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.020 Biomarker disease BEFREE 6-OHDA: 6-hydroxydopamine; AMPK: AMP-activated protein kinase; ATG: autophagy related; CAV1: caveolin 1; ER: endoplasmic reticulum; FN1: fibronectin 1; GSH: glutathione; IDE: insulin degrading enzyme; IL: interleukin; LDH: lactate dehydrogenase; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; MEF: mouse embryonic fibroblast; MTOR: mechanistic target of rapamycin kinase; NAC: N-acetyl-L-cysteine; PARK7/DJ-1: Parkinsonism associated deglycase; PD: Parkinson disease; RPS6KB1/p70S6K: ribosomal protein S6 kinase B1; RPN1: ribophorin I; ROS: reactive oxygen species; ULK1: unc-51 like autophagy activating kinase 1; WT: wild-type. 30112966 2018
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.020 Biomarker disease LHGDN These data highlight a genomic region in the proximity of IDE that may contribute to AD and PD in a similar manner. 15088150 2004
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.020 Biomarker disease BEFREE These data highlight a genomic region in the proximity of IDE that may contribute to AD and PD in a similar manner. 15088150 2004