IDE, insulin degrading enzyme, 3416

N. diseases: 71; N. variants: 19
Disease: Impaired glucose tolerance ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		0.030 AlteredExpression phenotype BEFREE L-IDE-KO mice exhibited higher (~20%) fasting and non-fasting plasma glucose levels, glucose intolerance and insulin resistance. 30098324 2018
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		0.030 GeneticVariation phenotype BEFREE However, the inhibition of IDE can also lead to glucose intolerance. 26651592 2016
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		0.030 GeneticVariation phenotype BEFREE Homologous deletion of IDE gene resulted in hyperinsulinemia and glucose intolerance in a rat model of type 2 diabetes mellitus. 17913278 2008