IGF2, insulin like growth factor 2, 3481

N. diseases: 604; N. variants: 19
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
0.320 AlteredExpression group BEFREE Copy-number and RNA-seq data analysis identified amplifications and corresponding overexpression of IGF2 in a subset of colon tumours. 22895193 2012
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
0.320 Biomarker group CTD_human Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. 15057734 2004
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
0.320 GeneticVariation group BEFREE Using an IGF-II radioimmunoassay, we have now detected high levels of both 10-kDa and 7.5-kDa IGF-II species (2,370 ng/g) in a right colon tumor showing a 800-fold IGF-II gene over-expression in comparison to the normal adjacent tissue. 1713573 1991