IGF2R, insulin like growth factor 2 receptor, 3482

N. diseases: 166; N. variants: 18
Disease: Adenoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001430
Disease: Adenoma
Adenoma 		0.030 GeneticVariation group BEFREE We examined the association of circulating levels of IGF-1, IGFBP-3 and IGFBP-1, and SNPs in the IGF-1 receptor (IGF1R), IGF-2 receptor (IGF2R), and insulin receptor genes with risk of adenomas in a sample of 410 incident adenoma cases and 1,070 controls from the Case Transdisciplinary Research on Energetics and Cancer (TREC) Colon Adenomas Study. 24194259 2014
CUI: C0001430
Disease: Adenoma
Adenoma 		0.030 AlteredExpression group LHGDN Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors. 18611974 2008
CUI: C0001430
Disease: Adenoma
Adenoma 		0.030 GeneticVariation group BEFREE Recently, it was reported in the United States that loss of heterozygosity (LOH) and mutations in exons 27, 28, and 31 of the M6P/IGF2R gene are frequent in hepatocellular carcinomas (HCCs) and adenomas. 10347113 1999