IGF2R, insulin like growth factor 2 receptor, 3482

N. diseases: 166; N. variants: 18
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.040 AlteredExpression group LHGDN Differential expression of the mannose 6-phosphate/ insulin-like growth factor-II receptor in human breast cancer cell lines of different invasive potential. 12165733 2002
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.040 Biomarker group BEFREE The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene. 9516081 1998
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.040 GeneticVariation group BEFREE Recently, a high frequency of loss of heterozygosity with concomitant mutations in the remaining allele has been shown to occur at the M6P/IGF2R locus (i.e., 6q26-q27) in both human liver and breast tumors, suggesting that this gene functions as a tumor suppressor. 9034167 1997
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.040 GeneticVariation group BEFREE Using the polymerase chain reaction, we utilized two polymorphisms in the 3' untranslated region of M6P/IGF2r to screen breast tumors for LOH. 8649861 1996