FAS, Fas cell surface death receptor, 355

N. diseases: 754; N. variants: 47
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 Biomarker group CTD_human Genomic landscape of cutaneous T cell lymphoma. 26192916 2015
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 AlteredExpression group LHGDN Serum levels of sFas and sFasL during chemotherapy of lung cancer. 17704746 2007
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 GeneticVariation group LHGDN Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer. 15937082 2005
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 GeneticVariation group LHGDN Fas A670G polymorphism, apoptotic capacity in lymphocyte cultures, and risk of lung cancer. 14512182 2003
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 AlteredExpression group LHGDN Soluble Fas in malignant pleural effusion and its expression in lung cancer cells. 12824926 2003
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 GeneticVariation group LHGDN Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer. 12037669 2002
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 Biomarker group BEFREE These findings suggest that the Fas protein is reduced or not present on the cell surface in the primary lung tumors and is sequestered within A549 tumorigenic lung cells, and these alterations directly affect the cells resistance to Fas-mediated apoptosis. 9486981 1998