IL2, interleukin 2, 3558

N. diseases: 950; N. variants: 5
Disease: Hyperactive behavior ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0424295
Disease: Hyperactive behavior
Hyperactive behavior 		0.030 Biomarker phenotype BEFREE We found that intrarenal Treg show phenotypic signs that are reminiscent of IL-2 deprivation in parallel to a progressive hyperactivity of intrarenal conventional CD4+ T cells (Tcon). 31614462 2019
CUI: C0424295
Disease: Hyperactive behavior
Hyperactive behavior 		0.030 Biomarker phenotype BEFREE IL-2 mediates NK cell proliferation but not hyperactivity. 29256180 2018
CUI: C0424295
Disease: Hyperactive behavior
Hyperactive behavior 		0.030 AlteredExpression phenotype BEFREE This provides a mechanism for their increased response to IL-2 and supports claims that elevated soluble IL-2R alpha serum levels reflect gut T-cell hyperactivity in this disease. 8425687 1993