Behcet Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
IL-8 could act as a novel target for the treatment of BD theoretically and probably play a key role in disease recovery.
|
31695669 |
2019 |
Behcet Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Upon stimulation with SAA, monocytes obtained from both HC and BD groups released large amounts of IL-8, IL-6, TNF-α, IL-1β and IFN-α.
|
30385329 |
2018 |
Behcet Syndrome
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We demonstrated that the frequencies of IL-8 haplotypes were significantly different with BD patients than control group.
|
27101127 |
2016 |
Behcet Syndrome
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The single nucleotide polymorphisms of the IL-6 and IL-8 receptor genes and the TNF-alpha gene analysed here do not appear to be associated with Behçet's disease.
|
19026125 |
2009 |
Behcet Syndrome
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to develop tools as reliable as IL-8 levels in defining BD severity.
|
19187295 |
2009 |
Behcet Syndrome
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms in interleukin-10, IL-8 and CD28 genes were also associated with Behçet's disease.
|
18281862 |
2008 |
Behcet Syndrome
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
In conclusion, we found a significant difference in the distribution of IL-8 gene haplotypes between patients with BD and healthy controls.
|
17257314 |
2007 |
Behcet Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
In our previous studies, we found higher synovial fluid (SF) levels of angiogenic ELR(+) CXC chemokines such as CXCL1, CXCL5, CXCL6 and CXCL8, which play an important role in neutrophil migration and angiogenesis, and more abundant synovial CXCR2 chemokine receptor expression in patients with rheumatoid arthritis (RA) than those with Behçet's disease (BD), familial Mediterranean fever and osteoarthritis (OA).
|
17265155 |
2007 |
Behcet Syndrome
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
These results suggest that the genetic polymorphisms of proinflammatory chemokine IL-8 can contribute to the pathogenesis of BD.
|
17257314 |
2007 |
Behcet Syndrome
|
0.400 |
Biomarker
|
disease |
LHGDN |
Serum interleukin-8 as a serologic marker of activity in Behçet's disease.
|
16101867 |
2005 |
Behcet Syndrome
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
These results suggest that the IL-8 gene -353 A/G, +1530 T/C, and +3331 A/G and the CXCR2 gene +785 C/T and +1208 T/C polymorphisms have no role in the increased expression of IL-8 in BD.
|
15630732 |
2005 |
Behcet Syndrome
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We observed important increases in the expression of interleukin-8 (IL-8) ( approximately 700-fold), monocyte chemoattractant protein 1 ( approximately 65-fold), interferon-gamma ( approximately 71-fold), and IL-12 ( approximately 69-fold) messenger RNA in BD lesions compared with normal skin.
|
15248229 |
2004 |
Behcet Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our results suggest that the cellular source of IL-8 is diverse in BD with a possible major contribution by lymphocytes.
|
10812500 |
2000 |
Behcet Syndrome
|
0.400 |
Biomarker
|
disease |
CTD_human |
Neutrophil adhesion to endothelial cells and factors affecting adhesion in patients with Behçet's disease.
|
8712863 |
1996 |