|
Depression, Bipolar
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Interleukin (IL)-1β, tumor necrosis factor (TNF)-α, soluble TNF receptor (sTNFR)1, IL-12 and IL-10 were significantly higher in MDD than in BD, whereas IL-6, sTNFR2, IL-18, IL-33, ST2 (IL1R Like 1) and KLOTHO were significantly higher in BD than in MDD.
|
31693974 |
2020 |
|
Bone Marrow Diseases
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Given that gut dysbiosis could augment the proinflammatory status of the intestines leading to a variety of acute inflammatory diseases, bone marrow-derived macrophages were stimulated with cecal content from dysbiotic mice showing a higher expression of proinflammatory cytokines and lower expression of IL-10.
|
31682032 |
2020 |
|
Congenital heart disease
|
0.010 |
Biomarker
|
group |
BEFREE |
The importance of the anti-inflammatory mediators IL-1ra and IL-10, as well as cytokines Epo and VEGF, which could impact on the pathogenesis and outcomes in congenital heart disease (CHD) which is more prevalent in DS, are less well known.
|
31785499 |
2020 |
|
Polyarthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
RSVO also prevented polyarthritis-related cartilage destruction, an effect that might rely on the inhibition of the pro-inflammatory cytokine interleukin-6 (IL-6), associated with an increase of the anti-inflammatory cytokine interleukin-10 (IL-10).
|
31720991 |
2020 |
|
Visceral Pain
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Endogenous control of visceral pain by opioids locally produced in inflamed mucosa was assessed in IL-10-deficient mice.
|
31588671 |
2020 |
|
Parkinsonian Disorders
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Elevated levels of pro-inflammatory RANTES or MCP-1 and decreased levels of anti-inflammatory IL-10 were found to associate with Parkinsonism and a more rapid disease progression, indicated by longitudinal measurements of either MMSE or ADCS-ADL decline.
|
31559531 |
2020 |
|
Chronic Chagas' disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Serum IL-10 Levels and Its Relationship with Parasitemia in Chronic Chagas Disease Patients.
|
31701864 |
2020 |
|
Seizure, Febrile, Complex
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Cerebrospinal fluid levels of granzyme A were significantly higher, and those of TNF-α and IL-1RA were significantly lower in the AE group than in the cFS group; however, no significant differences in the levels of granzyme B, IFN-γ, IL-1β, IL-4, IL-6, IL-8, and IL-10 were observed between the 2 groups.
|
31709864 |
2020 |
|
Recurrent respiratory papillomatosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Plasma IL-10 as well as IL-10 secreted by mDC was higher in JORRP patients compared with healthy control.
|
31726188 |
2020 |
|
After-cataract
|
0.010 |
Biomarker
|
disease |
BEFREE |
In alcohol-fed mice, infiltrating CD11b<sup>+</sup> Ly-6C<sup>Low/-</sup> monocytes had reduced mRNA expression of matrix metalloproteinase 13 and matrix metalloproteinase 9 and increased expression of tissue inhibitor of matrix metalloproteinase 1, Tgfb1, and interleukin-10 during resolution of CF.
|
31206736 |
2020 |
|
Acute encephalopathy
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Cerebrospinal fluid levels of granzyme A were significantly higher, and those of TNF-α and IL-1RA were significantly lower in the AE group than in the cFS group; however, no significant differences in the levels of granzyme B, IFN-γ, IL-1β, IL-4, IL-6, IL-8, and IL-10 were observed between the 2 groups.
|
31709864 |
2020 |
|
Gastrointestinal inflammation
|
0.010 |
Biomarker
|
disease |
BEFREE |
IL-10 is an immune regulatory cytokine and its genetic defect leads to gastrointestinal inflammation in both human and mouse.
|
31755523 |
2020 |
|
Anthracosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
HBV: hepatitis B virus; HCC hepatocellular carcinoma; TNFSF10: tumor necrosis factor superfamily member 10; ATG5: autophagy-related protein 5; DNA: deoxyribonucleic acid; LDR-PCR: ligase detection reactions-polymerase chain reaction; PCR: polymerase chain reaction; SLE: systemic lupus erythematosus; BD: Behçet's disease; IL-10: interlukin-10; LPS: lipopolysaccharide; PBMC: peripheral blood mononuclear cells; CWP: coal workers' pneumoconiosis; TNF-α: tumor necrosis factor-α.
|
30907204 |
2019 |
|
Bronchiectasis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, remarkable increased level of IL17 and IL-6 and decreased level of IL-10 and TGF-ß were observed in the bronchiectasis combined COPD than in pure COPD (All P<0.05).
|
31503552 |
2019 |
|
Burning Mouth Syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
IL-10 levels were measured in three studies that reported no significant differences in the levels between Burning Mouth Syndrome and healthy controls.
|
31132870 |
2019 |
|
Chorioamnionitis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
TLR2 and TLR4-mediated TNF-α, IL-1β, IL-6, IL-12p70, and IL-10 production in vitro increased over the first month of life in preterm infants and were positively correlated with leukocyte-adjusted cAMP levels and reduced by exposure to chorioamnionitis.
|
31578034 |
2019 |
|
Coxsackievirus Infections
|
0.010 |
Biomarker
|
group |
BEFREE |
IL-10-producing B cells attenuate cardiac inflammation by regulating Th1 and Th17 cells in acute viral myocarditis induced by coxsackie virus B3.
|
31493482 |
2019 |
|
Diabetic Neuropathies
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Our study assessed the association between ACE I>D, MTHFR C677T, MTHFR 1298A/C, GPx-1 rs1050450, CAT -262C/T, GSTM1, GSTT1, and IL-10 -1082G/A polymorphisms and DN risk.
|
31557408 |
2019 |
|
Distemper
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
IL-10 mRNA expression was dramatically enhanced at 12-36 h after CDV infection.
|
30999020 |
2019 |
|
Dry Eye Syndromes
|
0.010 |
Biomarker
|
disease |
BEFREE |
Compared with healthy controls, interleukin-6 was significantly higher (<i>p</i> = 0.0001) in patients with primary open-angle glaucoma and interleukin-1β (<i>p</i> = 0.0144), interleukin-6 (<i>p</i> < 0.0001), and interleukin-10 (<i>p</i> = 0.0392) were higher in patients with dry eye disease.
|
30175615 |
2019 |
|
Fibromuscular Dysplasia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The results of total IgG, IgG1, IgG2a levels and secretion of IFN-γ, IL-4 and IL-10 revealed that immune responses were enhanced when the epitope recombinant vaccine of FMD virus coupled with IL-2 and FcIgG.
|
31004723 |
2019 |
|
Flushing
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Interferon-stimulated genes (ISGs: ISG15 and OAS1) were increased in both PMNs and PBMCs, with up-regulation of PTGES and anti-inflammatory cytokines (TGFB1 and IL10) expressions at Day-7 of post-inseminations in cows, when compared to those at Day-7 in non-inseminated cows.
|
30376193 |
2019 |
|
Fuchs' heterochromic cyclitis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We observed a significant decrease in IL-10 levels in the AqH of patients with BU and a significant increase in VEGF levels in the AqH of patients with FUS compared to controls.
|
31065903 |
2019 |
|
Hyperemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
To characterize the preclinical model the parameters more used include body weight, stool consistency and morbidity, inflammatory biomarkers like interferon (IFN)-γ, myeloperoxidase (MPO), tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-10, presence of ulcers, thickness or hyperemia in the colon, and histological evaluation of the inflammation.
|
31581545 |
2019 |
|
Hyperinsulinism
|
0.010 |
Biomarker
|
disease |
BEFREE |
When combined with HI + IL-10 or IL-10 alone it decreased also significantly hAC proliferation compared to NG<sub>w/o</sub>.
|
30759730 |
2019 |