|
Dermatitis, Atopic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The current evidence does not support a strong genetic relationship between IL-10 -1082 A/G, - 819 T/C and - 592 A/C polymorphisms and the susceptibility to atopic dermatitis.
|
31101031 |
2019 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Moreover, ICOS<sup>+</sup> Tregs showed reduced production of interleukin-10, suggesting impaired immunosuppression in AD.
|
30515983 |
2019 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Low Interleukin 10 Production at Birth Is a Risk Factor for Atopic Dermatitis in Neonates with Bifidobacterium Colonization.
|
30205386 |
2019 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
BEFREE |
The production of IL-6 and IL-10 was impaired by Pam3Cys in supernatants from AD skin.
|
29672867 |
2018 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
BEFREE |
The results showed promoting effects of auraptene on T cell subsets toward Th<sub>1</sub> (IFN-γ) and T<sub>reg</sub> (IL-10), which suggest its therapeutic value for treatment of Th<sub>2</sub> cells predominant diseases including allergic disease such as asthma and atopic dermatitis as well as cancers.
|
29747740 |
2018 |
|
Dermatitis, Atopic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The allele and genotype frequencies of genes encoding for IL-10 and TGF-β1 were investigated in 89 patients with atopic dermatitis in comparison with 138 in the control group using the PCR-SSP method.
|
29310944 |
2018 |
|
Dermatitis, Atopic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We also investigated the inhibitory capacity of WIKIM30 on the development of 2,4-dinitrochlorobenzene-induced atopic dermatitis (AD), a Th2-dominant allergic disease in mice.Oral administration of <i>L. sakei</i> WIKIM30 significantly reduced AD-like skin lesions and serum immunoglobulin E and IL-4 levels while decreasing the number of CD4<sup>+</sup> T cells and B cells and the levels of Th2 cytokines (IL-4, IL-5, and IL-13) in peripheral lymph nodes and enhancing Treg differentiation and IL-10 secretion in mesenteric lymph nodes.
|
30154801 |
2018 |
|
Dermatitis, Atopic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The increased level of SP, in atopic dermatitis, induces the release of interferon (IFN)-γ, interleukin (IL)-4, tumor necrosis factor (TNF)-α, and IL-10 from the peripheral blood mononuclear leukocytes.
|
29713744 |
2018 |
|
Dermatitis, Atopic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Our results showed that ozonated oil could suppress inflammation in an AD murine via decreasing Th2-dominant cytokines response and increasing IL-10 expression.
|
29466894 |
2018 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our findings indicate a potential role of IDEC-like in the maintenance of inflammation in atopic dermatitis patients; moreover, IDEC-like may exert a regulatory impact on T cells of AD individuals through IL-10, often induced by agonist mimicking single stranded RNA virus.
|
28083892 |
2017 |
|
Dermatitis, Atopic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
To investigate TLR2 and TLR4 expression on PB monocytes during AD exacerbation and to assess the relationships between TLR expressions with AD clinical severity and with serum interleukin (IL) 4, IL-10, and IL-17a levels.
|
26534745 |
2016 |
|
Dermatitis, Atopic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association between the IL10 -1082A>G (rs1800896) single-nucleotide polymorphism and atopic dermatitis: a systematic review and meta-analysis.
|
23857017 |
2014 |
|
Dermatitis, Atopic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Mothers who had atopic dermatitis had significantly decreased levels of IL-10 (p = 0.044) in breast milk.
|
23980846 |
2013 |
|
Dermatitis, Atopic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Protective cytokine polymorphisms for AD for seven cytokine genotypes (IL-4 -1098/G:T, TGFbeta cdn25/G:G, IL-4 -33/C:C, IL-1alpha -889/C:C, IFNgamma +874/A:A, IL-10 -1082/A:A, IL-1beta -511/C:C), one cytokine diplotypes, two cytokine haplotypes, and four cytokine alleles were also found.
|
22427475 |
2012 |
|
Dermatitis, Atopic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In our study, genotypes of 7 polymorphisms--LL-4 -1098G/T and -590C/T, IL-6 -174C/G and nt565A/G, and IL-10 -1082A/G, -819C/T, and -592A/C were significantly associated with atopic AD (P < .05).
|
22533231 |
2012 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
BEFREE |
IL-10 production was significantly decreased in the supernatants from both the HCs and patients with AD after CRH treatment.
|
22000570 |
2012 |
|
Dermatitis, Atopic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
FLG mutation, alone and in combination with certain IL-10 or IL-13 polymorphisms, enhances the risk for the development of AD in the Polish population.
|
21426411 |
2011 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
BEFREE |
After adjusting for multiple tests, the association between IL13 130 and IgE and the interactive effects of IL10-1082 on current rhinitis and IL8 781 on atopic eczema were significant by controlling a false-positive rate of 0.05 and 0.10, respectively.
|
21749458 |
2011 |
|
Dermatitis, Atopic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
SNPs at positions -3575, -2849, -2779, -2763, -1082, -851, -819 and -592 in the IL10 promoter region were genotyped in individuals with atopic dermatitis (n= 47) and nonatopic control subjects (n= 40) using polymerase chain reaction-based techniques and induced heteroduplex generator (IHG) analysis.
|
19552724 |
2009 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
CTD_human |
Peroxisome proliferator-activated receptor alpha regulates skin inflammation and humoral response in atopic dermatitis.
|
18249437 |
2008 |
|
Dermatitis, Atopic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
IL-10 promoter polymorphisms are associated with the phenotype of AD in children.
|
17188628 |
2007 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Increased lipopolysaccharide-induced tumour necrosis factor-alpha, interferon-gamma and interleukin-10 production in atopic dermatitis.
|
17596153 |
2007 |
|
Dermatitis, Atopic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Interleukin-10 downregulates anti-microbial peptide expression in atopic dermatitis.
|
16185274 |
2005 |
|
Dermatitis, Atopic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Interleukin-10 haplotype associated with total serum IgE in atopic dermatitis patients.
|
16076299 |
2005 |
|
Dermatitis, Atopic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Having a dog in infancy is associated with higher IL-10 and IL-13 cytokine secretion profiles and reduced allergic sensitization and atopic dermatitis.
|
14767447 |
2004 |