|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
For the treatment of myocardial infarction (MI), interleukin-10 (IL-10) is encapsulated in microgels and released from composites.
|
30259658 |
2019 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
Upregulation of plasma levels and cardiac gene expression levels of inflammatory cytokines such as interleukin (IL)-6 and IL-10 was seen in MI rats.
|
30128816 |
2019 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
IL-10 and other pro-inflammatory interleukins were analyzed in 90 subjects divided into 3 groups: group 1 (n = 30), patients with MetS without severe CAD; group 2 (n = 30), patients with MetS and severe CAD (history of myocardial infarction or revascularization performed through surgery or percutaneous transluminal coronary angioplasty with or without stent placement); and group 3 (n = 30), healthy individuals.
|
31075237 |
2019 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
Compared with control group, the levels of heart rate, left ventricular end-diastolic pressure, TNF-α, and IL-6 were increased in each group of rats with MI (all p < 0.05), while the levels of systolic blood pressure, diastolic blood pressure, mean arterial pressure, left ventricular systolic pressure, and IL-10 were significantly decreased (all p < 0.05).
|
31218464 |
2019 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
Gambogic acid suppressed the activation of interleukin (IL)-6 and tumor necrosis factor-α, and increased IL-10 levels in MI rats.
|
29434760 |
2018 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
Although both interleukin (IL)-4 and IL-10 were reported to promote CD206<sup>+</sup> macrophage-mediated cardiac repair after MI, IL-10- but not IL-4-stimulated CD11b<sup>+</sup>Ly6G<sup>-</sup> cells could differentiate into OPN-producing galectin-3<sup>hi</sup>CD206<sup>+</sup> macrophages and showed enhanced phagocytic ability.
|
29967195 |
2018 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
Consistently, the implantation of Ad.IL10-MSCs into MI animals resulted in more reductions in myocardial infarct size, cardiac impairment, and cell apoptosis, compared to the individual treatments of either MSC or IL10 administration.
|
28322445 |
2018 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
We found that synovial fluid levels of VEGF and IL-6 were significantly higher in patients with OA than in patients with MI, and IL-10 was lower in patients with OA compared to MI patients (p<0.05).
|
28810626 |
2017 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation.
|
28439731 |
2017 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Our study found that the IL-10 -1082A/G polymorphism plays an important role in influencing the development of MI.
|
26505348 |
2015 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
GoM allowed to identify a population of subjects negative for IL-10 -824T allele, 74.4% of which were diabetic patients characterised by vascular damages (Chronic kidney failure and/or Myocardial Infarction), reduction of haematocrit, increase of blood urea nitrogen, creatinin and monocyte levels.
|
20388104 |
2010 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
IL-10 expression was higher in MI-G and lower in MI-GM than in MI-C animals.
|
18832728 |
2008 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
These results suggest that BM-MNCs mediate cardiac protection after myocardial infarction and this is, at least in part, dependent on IL-10.
|
18566343 |
2008 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
In patients, IL-10 predicted a crude risk increase of death/MI, with the highest risk observed in the fourth quartile (adjusted odds ratio 1.7 (95% confidence interval 1.2 to 2.3)).
|
17690160 |
2008 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
We investigated variation in inflammation-related genes - interleukin (IL)-1beta, IL-6, C-reactive protein (CRP), IL-10, IL-18, and the tumor necrosis factor (TNF) superfamily [lymphotoxin(LT)-alpha, TNF-alpha, LT-beta] - with respect to nonfatal incident myocardial infarction (MI) or ischemic stroke risk.
|
17981284 |
2008 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
In addition, a predominance of the -1082ACC/ATA IL-10 genotype in the myocardial infarction group compared with the unstable angina group and the -874 A/A IFN-gamma genotype in the stable angina group compared with the unstable angina and the myocardial infarction group, was found.
|
19005292 |
2008 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
LHGDN |
Acute myocardial infarction and proinflammatory gene variants.
|
18056971 |
2007 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
In our study, association of interleukin-10 (IL-10) and CD14 polymorphisms and environmental factors with the risk of myocardial infarction was studied.
|
17617027 |
2007 |
|
Myocardial Infarction
|
0.500 |
AlteredExpression
|
disease |
LHGDN |
In patients with ST-se AMI, the serum IL-10 level is a major independent predictor of 30-day mortality and should be used for early risk stratification following acute myocardial infarction.
|
17587715 |
2007 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
CTD_human |
Effects of carvedilol on cardiac cytokines expression and remodeling in rat with acute myocardial infarction.
|
16310260 |
2006 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
BEFREE |
In this paper we review the evidence for a possible role of genetic polymorphisms of the most important inflammatory cytokines (IL-6, TNF-alpha, IL-10) and immune receptors (CD14 receptor and TLR-4) in modulating the incidence or the prognosis of MI, with a special focus in ageing population.
|
16516951 |
2006 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
CTD_human |
Simvastatin regulates myocardial cytokine expression and improves ventricular remodeling in rats after acute myocardial infarction.
|
15883752 |
2005 |
|
Myocardial Infarction
|
0.500 |
Biomarker
|
disease |
LHGDN |
Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart disease.
|
15466015 |
2004 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
We investigated the possibility that single nucleotide polymorphisms of the genes encoding TNF-alpha (-863C/A, -308G/A), LT-alpha (252G/A), and IL-10 (-1082G/A, -819C/T, and -592C/A) are associated with the incidence of restenosis, death, or myocardial infarction (MI) after coronary stenting.
|
14572794 |
2003 |
|
Myocardial Infarction
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that IL-10 polymorphisms are not associated with an increased risk of myocardial infarction.
|
11168433 |
2001 |