IL12A, interleukin 12A, 3592

N. diseases: 261; N. variants: 7
Disease: Sjogren's Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.330 Biomarker disease BEFREE Rapamycin significantly altered the expression of several genes linked to Sjögren's syndrome pathogenesis, including major histocompatibility complex II, TNF-α, IFN-γ, and IL-12a, as well as Akt3, an effector of autophagy. 28122086 2017
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.330 Biomarker disease BEFREE Of particular relevance, was the significant association of SS with additional immune-related genes including IL12A, BLK, and CXCR5. 24657515 2014
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.330 Biomarker disease CTD_human Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome. 24097067 2013
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.330 AlteredExpression disease LHGDN Rates of infiltration by macrophages and dendritic cells and expression of interleukin-18 and interleukin-12 in the chronic inflammatory lesions of Sjögren's syndrome: correlation with certain features of immune hyperactivity and factors associated with high risk of lymphoma development. 18050195 2007