IL13, interleukin 13, 3596

N. diseases: 587; N. variants: 9
Disease: Renal Cell Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.360 GeneticVariation disease BEFREE In this study, the association between renal cell carcinoma (RCC) risk and single nucleotide polymorphisms (SNPs) on IL-4/IL-13/IL-4R was assessed. 30472377 2019
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.360 Biomarker disease CTD_human IL-13 and IL-4R may play an important role in the etiology of RCC. 22317767 2012
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.360 Biomarker disease BEFREE IL-13 and IL-4R may play an important role in the etiology of RCC. 22317767 2012
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.360 Biomarker disease BEFREE Metastases to the brain (4/12, i.e., lung adenocarcinomas and renal cell carcinoma) showed some binding of 125I-IL13. 11083073 2000
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.360 Biomarker disease BEFREE We also observed cooperativity phenomena in IL-13 and IL-13R interaction in control RCC (MLneo) cells, but not in cells transfected with gammac chain (MLgammac). 10388747 1999
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.360 Biomarker disease BEFREE Even though IL-13 and IL-4 are homologues and IL-4R and IL-13R have been proposed to share a receptor subunit, IL-4 did not compete for the cytotoxicity mediated by IL13-toxin on RCC. 8639793 1996
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.360 AlteredExpression disease BEFREE We report, for the first time, that IL-4 and IL-13 can up-regulate protein expression as well as enzymatic activity of both the peptidases on renal carcinoma cells and renal tubular epithelial cells in culture. 7743667 1995