INS, insulin, 3630

N. diseases: 405; N. variants: 37
Disease: Alzheimer's Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.530 Biomarker disease BEFREE <b>Abbreviations</b>: AD: Alzheimer disease; BM: basement membrane; BWM: body wall muscle; CEP: cephalic sensilla; CLEM: correlative light and electron microscopy; CTNS-1: cystinosin (lysosomal protein) homolog; DA: dopaminergic; DAF-2: abnormal dauer formation; ECM: extracellular matrix; FLIM: fluorescence lifetime imaging microscopy; fps: frames per second; GFP: green fluorescent protein; HPF: high pressure freezing; IGF1: insulin-like growth factor 1; INS: insulin; KD: knockdown; LMP: lysosomal membrane permeabilization; MVB: multivesicular body; NOC: nocodazole; PD: Parkinson disease; RFP: red fluorescent protein; RNAi: RNA interference; sfGFP: superfolder GFP; SNCA: synuclein alpha; TEM: transmission electron microscopy; TNTs: tunneling nanotubes; TCSPC: time correlated single photon counting; YFP: yellow fluorescent protein. 31354022 2020
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.530 Biomarker disease RGD Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein. 17448147 2007
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.530 Biomarker disease CTD_human Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes? 15750215 2005
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.530 GeneticVariation disease LHGDN The insulin gene VNTR polymorphism in Alzheimer's disease: results of a pilot study. 12111440 2002
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.530 Biomarker disease CTD_human Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. 9443474 1998
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.530 Biomarker disease BEFREE Analysis of HLA-DQB1 alleles in DR4+ Addison's patients with diabetes mellitus (N = 6) and without IDDM (14 of 18 individuals tested) revealed that the HLA-DQw8 allele (DQB1*0302) was significantly increased in AD patients with IDDM (chi 2 = 13.5; p = 0.001); conversely, a clustering of the HLA-DQw7 allele was detected in DR4+ Addison's patients without IDDM. 1871764 1991