Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.050 AlteredExpression group BEFREE SHIP2 activity is elevated in glomeruli of patients with T2D receiving nonmetformin medication, but not in patients receiving metformin, compared with people without diabetes. 30321069 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.050 Biomarker group BEFREE The Src homology 2-containing inositol 5-phosphatase 2 (SHIP2) is implicated in diabetes, arthrosclerosis, and cancer. 26201869 2016
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.050 GeneticVariation group BEFREE Two INPPL1 single-nucleotide polymorphisms, rs2276048 (silent mutation) and rs2276047 (intronic), were associated with the metabolic syndrome in men with odds ratios of 0.23 (95% CI 0.11-0.45, P = 2.1 × 10(-5) ), and 0.37 (0.21-0.65, P = 0.001), adjusted for age, duration of diabetes and history of smoking. 22486725 2012
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.050 GeneticVariation group BEFREE Inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) is a negative regulator of insulin signalling and has previously been found to be associated with hypertension, obesity and type 2 diabetes in a cohort of families with diabetes in the UK presenting features of metabolic syndrome. 17557929 2007
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.050 GeneticVariation group BEFREE The SNPs in the SHIP2 gene promoter and the 5'-UTR may account partly for the IFG and may be a marker for the risk of diabetes. 16804414 2006