PDX1, pancreatic and duodenal homeobox 1, 3651

N. diseases: 185; N. variants: 22
Disease: Nesidioblastosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027773
Disease: Nesidioblastosis
Nesidioblastosis 		0.020 Biomarker disease BEFREE Examination of pancreatic tissue from Pdx-1-Aurora A transgenic mice revealed abnormalities, such as mild islet cell hyperplasia, lymphocytic infiltration, and general dysplasia between ductal/islet cell interfaces. 18815537 2008
CUI: C0027773
Disease: Nesidioblastosis
Nesidioblastosis 		0.020 AlteredExpression disease BEFREE Impaired expression of transcription factor IUF1 in a pancreatic beta-cell line derived from a patient with persistent hyperinsulinaemic hypoglycaemia of infancy (nesidioblastosis). 9280302 1997