AR, androgen receptor, 367

N. diseases: 854; N. variants: 163
Disease: Alopecia, Male Pattern ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 Biomarker disease BEFREE Comparative full transcriptome profile analysis of the hair bulb region of normal and miniaturized hair follicles from vertex and occipital region in males with and without androgenetic alopecia revealed that next to the androgen receptor as well the retinoid receptor and particularly the PPAR pathway is involved in progressive hair miniaturization. 31217429 2019
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 AlteredExpression disease BEFREE In this commentary, we use microcompetition to explain how common latent viruses can cause transcription factor deficiency, overexpression of 5α-reductase and AR, and male-pattern baldness. 30019525 2018
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 AlteredExpression disease BEFREE This review describes recent studies on the role of androgens and androgen receptor (AR) transactivation activity in modulating the Wnt/β-catenin signaling in the dermal papilla cells of the balding scalp in androgenetic alopecia. 29549490 2018
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer. 24665929 2015
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE Our results do not confirm a possible correlation or linkage disequilibrium between the CAG/GGC haplotypes of the AR gene and androgenetic alopecia in Mexican brothers. 26178169 2015
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 Biomarker disease BEFREE It is known that baldness caused by androgenetic alopecia is involved with androgen and the androgen receptor. 23955654 2013
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 Biomarker disease BEFREE These results define androgen/androgen receptor signaling as an accelerator of premature senescence in dermal papilla cells and suggest that the androgen/androgen receptor-mediated DNA damage-p16(INK4a) axis is a potential therapeutic target in the treatment of androgenetic alopecia. 24244503 2013
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 AlteredExpression disease BEFREE Increased androgen receptor messenger RNA in frontal-parietal hair follicles of women with androgenetic alopecia. 23479164 2013
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease GWASDB Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases. 22693459 2012
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE Androgen receptor gene polymorphisms and risk for androgenetic alopecia: a meta-analysis. 21981665 2012
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 Biomarker disease BEFREE Androgen and androgen receptor (AR) may play important roles in several skin-related diseases, such as androgenetic alopecia and acne vulgaris. 22829074 2012
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE We previously reported greater therapeutic efficacy of finasteride in Japanese male androgenetic alopecia (MAGA) patients in cases where the CAG repeats of the androgen receptor (AR) gene were short. 21352305 2011
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE Therapeutic hotline. Genetic variations in the androgen receptor gene and finasteride response in women with androgenetic alopecia mediated by epigenetics. 21410621 2011
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE Evidence for two independent functional variants for androgenetic alopecia around the androgen receptor gene. 21073542 2010
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE Polymorphism of the androgen receptor gene was first identified in association with androgenetic alopecia. 20426708 2010
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE The rs6152G/A AR gene polymorphism has been reported to be associated with male pattern baldness (MPB), which is a common characteristic of males in PCOS families. 20450840 2010
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 Biomarker disease BEFREE Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness. 19373488 2009
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 Biomarker disease BEFREE Evaluation of androgen receptor gene as a candidate gene in female androgenetic alopecia. 19538365 2009
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE Androgen receptor copy number variation and androgenetic alopecia: a case-control study. 19340294 2009
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)). 18849991 2008
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE Baldness and the androgen receptor: the AR polyglycine repeat polymorphism does not confer susceptibility to androgenetic alopecia. 17256155 2007
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE We analyzed a silent polymorphism in the androgen receptor gene (AR) in a group of 41 bald males and 39 non-bald males, and found a significant association (p < 0.0026), thus confirming the previously reported association between MPB and the AR gene. 16172040 2006
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 AlteredExpression disease BEFREE Expression of androgen receptor coactivator ARA70/ELE1 in androgenic alopecia. 16115056 2005
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 GeneticVariation disease BEFREE Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia. 15902657 2005
CUI: C4083212
Disease: Alopecia, Male Pattern
Alopecia, Male Pattern 		0.500 Biomarker disease CTD_human Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia. 15902657 2005