LDLR, low density lipoprotein receptor, 3949

N. diseases: 336; N. variants: 1434
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Biomarker phenotype CTD_human Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis. 28899902 2017
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Therapeutic phenotype CTD_human Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis. 28899902 2017
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Therapeutic phenotype CTD_human Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits. 25619500 2015
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Biomarker phenotype CTD_human Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits. 25619500 2015
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Biomarker phenotype CTD_human Resveratrol increases the expression and activity of the low density lipoprotein receptor in hepatocytes by the proteolytic activation of the sterol regulatory element-binding proteins. 22153697 2012
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Therapeutic phenotype CTD_human Resveratrol increases the expression and activity of the low density lipoprotein receptor in hepatocytes by the proteolytic activation of the sterol regulatory element-binding proteins. 22153697 2012
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Biomarker phenotype CTD_human Mangifera indica L. extract (Vimang) and its main polyphenol mangiferin prevent mitochondrial oxidative stress in atherosclerosis-prone hypercholesterolemic mouse. 18450471 2008
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Therapeutic phenotype CTD_human Mangifera indica L. extract (Vimang) and its main polyphenol mangiferin prevent mitochondrial oxidative stress in atherosclerosis-prone hypercholesterolemic mouse. 18450471 2008
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Therapeutic phenotype CTD_human Anti-atherosclerotic effect of simvastatin depends on the presence of apolipoprotein E. 11947894 2002
CUI: C1563937
Disease: Atherogenesis
Atherogenesis
0.300 Biomarker phenotype CTD_human Anti-atherosclerotic effect of simvastatin depends on the presence of apolipoprotein E. 11947894 2002