LOX, lysyl oxidase, 4015

N. diseases: 328; N. variants: 14
Disease: Fibrosis, Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.340 Biomarker disease BEFREE Co-administration of resveratrol and beta-aminopropionitrile attenuates liver fibrosis development via targeting lysyl oxidase in CCl<sub>4</sub>-induced liver fibrosis in rats. 31724452 2019
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.340 Biomarker disease BEFREE In addition, ICAB inhibited hepatic stellate cells (HSCs) activation and the expressions of hepatic genes involved in liver fibrosis including LOX, TGF-β1, MCP-1, COL1α1 and TIMP-1. 30180301 2019
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.340 Biomarker disease BEFREE The lysyl oxidase (LOX) family has been reported to promote liver fibrosis. 30257391 2018
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.340 Biomarker disease CTD_human Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. 26396155 2016
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.340 AlteredExpression disease BEFREE In contrast, steady state levels of lysyl oxidase mRNA increased throughout the onset of hepatic fibrosis and appeared in parallel with the increased steady state levels of pro-alphaI (I) collagen mRNA. 10022501 1999