LPA, lipoprotein(a), 4018

N. diseases: 340; N. variants: 49
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE The cardiometabolic phenotype of 1098 T2DM patients was analyzed according to an FH of T2DM and/or EOCHD, including body composition, fasting insulinemia, insulin sensitivity, β-cell function (BCF), lipids, lipoprotein(a), high-density lipoprotein (HDL) number and functionality, and micro- and macrovascular complications. 30105804 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE The Ratio of Oxidized Lipoprotein(a) to Native Lipoprotein(a) and the Endothelial Function in Patients with Type 2 Diabetes Mellitus. 31623352 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Elevated Lipoprotein (a) and Risk of Poor Functional Outcome in Chinese Patients with Ischemic Stroke and Type 2 Diabetes. 29264843 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression disease BEFREE Elevated lipoprotein (a) levels are associated with the presence and severity of coronary artery disease in patients with type 2 diabetes mellitus. 30030022 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Association between lipoprotein(a) level and type 2 diabetes: no evidence for a causal role of lipoprotein(a) and insulin. 28866807 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Lipoprotein (a) is not significantly associated with type 2 diabetes mellitus: cross-sectional study of 1604 cases and 7983 controls. 28132096 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Some evidence suggests that serum lipoprotein[Lp](a) may be inversely linked to type-2 diabetes. 28633585 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation disease BEFREE For SNPs selectively associated with lipoprotein(a) concentrations, an allele score of 4-6 vs 0-2 had an odds ratio for type 2 diabetes of 1.03 (95% CI, 0.86-1.23). 28971985 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression disease BEFREE The study was conducted in order to evaluate the levels of Apo A - V proteins and markers of inflammation and OS in patients of T2DM with and without hypertriglyceridemia (HTG) and also to assess correlation between them. 28848612 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE The mixed benefit of low lipoprotein(a) in type 2 diabetes. 28899393 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression disease BEFREE Effect of diet-induced weight loss on lipoprotein(a) levels in obese individuals with and without type 2 diabetes. 28386638 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Association Between Serum Lipoprotein(a) and Diabetic Retinopathy in Han Chinese Patients With Type 2 Diabetes. 28472352 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Conflicting interactions of apolipoprotein A and high density lipoprotein cholesterol with microvascular complications of type 2 diabetes. 28934670 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Lipoprotein(a) and incident type-2 diabetes: results from the prospective Bruneck study and a meta-analysis of published literature. 28320383 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation disease BEFREE In conclusion, because various genes, LDLR, CETP, APOA5, Apo E, Apo B, and Apo A-I, are associated with the precipitation of CAD associated with T2DM, a personalized diet-gene intervention therapy may be advocated to reduce the disease precipitation. 25470794 2015
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE The association between circulating lipoprotein(a) and type 2 diabetes: is it causal? 24089516 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation disease BEFREE Low concentrations of lipoprotein(a) in plasma were associated with risk of type 2 diabetes, with adjusted odds ratios of 1·26 (1·09-1·45), 1·17 (1·01-1·36), 1·04 (0·90-1·21), and 1·05 (95% CI 0·90-1·22), respectively, for quintiles 1-4, compared with quintile 5 concentrations. 24622370 2013
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Lipoprotein(a) and homocysteine as genetic risk factors for vascular and neuropathic diabetic foot in type 2 diabetes mellitus. 21986921 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation disease BEFREE Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes. 21900290 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE We estimated high inverse statistical correlation between apo(a) size (kDa) and plasma lipoprotein(a) concentration in all study groups, patients with IDDM (p<0.001), patients with NIDDM (p<0.001), and healthy subjects (p<0.01). 12950147 2003
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation disease BEFREE To elucidate the association of lipoprotein(a) (Lp(a)) with diabetic retinopathy (DR), we studied the serum Lp(a) concentrations (n = 412), apolipoprotein(a) (apo(a)) phenotypes expressed by the number of kringle 4 (K4) repeats (n = 150), apo(a) gene genotypes (n = 161) of type 2 diabetes with or without DR. 12397529 2002
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation disease BEFREE Lipoprotein(a) (Lp(a)) with atherogenic and thrombotic properties has been frequently studied in diabetes, because a high cardiovascular risk has been reported both in type 1 and type 2 diabetes. 10804324 2000
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE In this study we assessed the relationship of lipoprotein(a) [Lp(a)] with diabetes status and with measures of glucose and insulin in a population of Mexican Americans having a high prevalence of non-insulin-dependent diabetes mellitus (NIDDM). 9714142 1998
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Lipoprotein (a) concentration and apolipoprotein (a) phenotype in subjects with type 2 diabetes mellitus. 11189206 1998
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Serum lipoprotein(a) concentrations and apolipoprotein(a) phenotypes in the families of NIDDM patients. 8786017 1995