LPL, lipoprotein lipase, 4023

N. diseases: 290; N. variants: 116
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.320 Biomarker disease BEFREE The knockdowns of PPARα and CD36 reversed the LPL-mediated suppression of HCV infection. 27665576 2017
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.320 Biomarker disease BEFREE The fact that treatment of HCV fraction with lipoprotein lipase (LPL) abolished infectivity indicates the essential role of lipoprotein's association with virus particle in the virus life cycle. 22440563 2011
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.320 Therapeutic disease CTD_human Our findings suggest that LPL mediates HCV cell entry by a mechanism similar to hepatic clearance of TRL from the circulation, promoting a non-productive virus uptake. 17517063 2007