|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association study of DRD2 and MAOA genes with subtyped alcoholism comorbid with bipolar disorder in Han Chinese.
|
23044341 |
2013 |
|
Bipolar Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Association study of DRD2 and MAOA genes with subtyped alcoholism comorbid with bipolar disorder in Han Chinese.
|
23044341 |
2013 |
|
Bipolar Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
We analyzed 62 genotyped variants within the selected genes (BDNF, NTRK2, SLC6A4, TPH2, P2RX7, DAOA, COMT, DISC1, and MAOA) against the presence of mood disorder, and in post-hoc analyses, specifically against bipolar disorder or major depressive disorder.
|
21438144 |
2011 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
To evaluate the controversial, putative associations between the three common polymorphisms [promoter variable number tandem repeat (uVNTR), T941G, (CA) repeat] of monoamine oxidase A (MAOA) and mood disorders (major depressive or bipolar disorders, BPD) by systematically meta-analyzing published case-control association studies.
|
20010318 |
2010 |
|
Bipolar Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
To evaluate the controversial, putative associations between the three common polymorphisms [promoter variable number tandem repeat (uVNTR), T941G, (CA) repeat] of monoamine oxidase A (MAOA) and mood disorders (major depressive or bipolar disorders, BPD) by systematically meta-analyzing published case-control association studies.
|
20010318 |
2010 |
|
Bipolar Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Our results suggest that MAOA polymorphisms do not play a major role in pathogenesis of BD or its clinical subtypes in Han Chinese.
|
18437281 |
2008 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that MAOA polymorphisms do not play a major role in pathogenesis of BD or its clinical subtypes in Han Chinese.
|
18437281 |
2008 |
|
Bipolar Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Furthermore, we performed a particular gene-gene interaction for the X-linked serotonergic genes (HTR2C and MAOA), and found no association among this intergenic haplotype combination and suicidal behaviour in bipolar disorder.
|
18504633 |
2008 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate MAOA gene variants in bipolar disorder by using a family-based association approach.
|
16958037 |
2007 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In order to test this hypothesis, we genotyped the 941T > G and the promoter VNTR polymorphisms in the MAOA gene and the Val 108/158 Met COMT polymorphism in 305 families with at least one member having bipolar disorder (BD).
|
15936529 |
2005 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Regarding MAOA, three meta-analyses with partially overlapping samples supported a modest effect of this gene in bipolar disorder in female Caucasians.
|
15727488 |
2005 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that MAOA gene variation may modulate the expression of some clinical aspects of severe mood disorders, especially in females, and support the existence of a genetic and aetiologic heterogeneity underlying the diagnoses of bipolar disorder and major depression.
|
15564894 |
2004 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The associations with the MAOA and serotonin transporter loci are consistent with previous data suggesting associations with susceptibility to bipolar affective disorder.Am.J. Med.Genet.(Neuropsychiatr.Genet.)96:36-42, 2000
|
10686549 |
2000 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Given the link between abnormalities in serotonergic neurotransmission and bipolar disorder, a candidate gene association approach was applied to study the involvement of the monoamine oxidase A (MAOA) gene, which codes for a catabolic enzyme of serotonin, in the susceptibility to bipolar disorder.
|
10831475 |
2000 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our results were not supportive of a major role of MAOA in the predisposition to bipolar disorder.
|
10335547 |
1999 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
This study examined whether this functional polymorphism of the MAOA gene is associated with the risk of developing mood disorders in a Japanese sample of 161 patients with bipolar disorder, 98 with unipolar depression, and 258 controls.
|
10483059 |
1999 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Associations of bipolar affective disorder in pooled male and female groups were found with the MAOA microsatellite in both the Caucasian (P < 0.02) and the Japanese (P < 0.02) meta-analyses.
|
10402508 |
1999 |
|
Bipolar Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
Recently, evidence for genetic association between the MAO-A gene and bipolar mood disorder was obtained in Caucasians.
|
9807650 |
1998 |
|
Bipolar Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
These data do not support the association of MAO-A or B with bipolar affective disorder but do demonstrate that undetected population stratification can be an important source of bias in case-control studies.
|
9342194 |
1997 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis.
|
8776592 |
1996 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder.
|
7485270 |
1995 |
|
Bipolar Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms.
|
7485269 |
1995 |