MAOA, monoamine oxidase A, 4128

N. diseases: 300; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.320 GeneticVariation disease BEFREE Studies have examined the interaction of MAOA genotype with childhood maltreatment in relation to depressive symptomatology and alcohol abuse with conflicting findings. 22030358 2012
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.320 Biomarker disease PSYGENET Low-activity MAOA genotype buffered against symptoms of dysthymia, major depressive disorder, and alcohol abuse for sexually abused white participants. 22030358 2012
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.320 GeneticVariation disease BEFREE For example, it has been shown that childhood maltreatment interacts with a monoamine oxidase A (MAOA) gene variant to predict antisocial behavior that is often associated with alcoholism, and an interaction between early life stress and a serotonin transporter promoter variant predicts alcohol abuse in nonhuman primates and depression in humans. 17347351 2006
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.320 Biomarker disease PSYGENET For example, it has been shown that childhood maltreatment interacts with a monoamine oxidase A (MAOA) gene variant to predict antisocial behavior that is often associated with alcoholism, and an interaction between early life stress and a serotonin transporter promoter variant predicts alcohol abuse in nonhuman primates and depression in humans. 17347351 2006