MAT2A, methionine adenosyltransferase 2A, 4144

N. diseases: 81; N. variants: 1
Disease: Liver and Intrahepatic Biliary Tract Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0279000
Disease: Liver and Intrahepatic Biliary Tract Carcinoma
Liver and Intrahepatic Biliary Tract Carcinoma 		0.040 Biomarker disease BEFREE Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer. 23588207 2013
CUI: C0279000
Disease: Liver and Intrahepatic Biliary Tract Carcinoma
Liver and Intrahepatic Biliary Tract Carcinoma 		0.040 PosttranslationalModification disease BEFREE In this study, we investigated the link between HIF-1α and MAT2A as a mechanism responsible for the change in genomic DNA methylation patterns in liver cancer under hypoxia conditions. 21460102 2011
CUI: C0279000
Disease: Liver and Intrahepatic Biliary Tract Carcinoma
Liver and Intrahepatic Biliary Tract Carcinoma 		0.040 Biomarker disease BEFREE Results from immunohistochemistry analyses of 37 pairs of HBV-associated liver cancer tissues/corresponding peritumor tissues showed that HBx and MAT2A are highly expressed in most liver tumor tissues. 21247894 2011
CUI: C0279000
Disease: Liver and Intrahepatic Biliary Tract Carcinoma
Liver and Intrahepatic Biliary Tract Carcinoma 		0.040 AlteredExpression disease BEFREE We showed a switch from MAT1A to MAT2A expression in human liver cancer, which facilitates cancer cell growth. 11208539 2001