MAT2A, methionine adenosyltransferase 2A, 4144

N. diseases: 81; N. variants: 1
Disease: Malignant neoplasm of liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.040 Biomarker disease BEFREE Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer. 23588207 2013
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.040 PosttranslationalModification disease BEFREE In this study, we investigated the link between HIF-1α and MAT2A as a mechanism responsible for the change in genomic DNA methylation patterns in liver cancer under hypoxia conditions. 21460102 2011
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.040 Biomarker disease BEFREE Results from immunohistochemistry analyses of 37 pairs of HBV-associated liver cancer tissues/corresponding peritumor tissues showed that HBx and MAT2A are highly expressed in most liver tumor tissues. 21247894 2011
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.040 AlteredExpression disease BEFREE We showed a switch from MAT1A to MAT2A expression in human liver cancer, which facilitates cancer cell growth. 11208539 2001