Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 GeneticVariation disease BEFREE Therapy-related B-lymphoblastic leukemia associated with Philadelphia chromosome and MLL rearrangement: Single institution experience and the review of the literature. 26259760 2016
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 GeneticVariation disease BEFREE Therapy-related B lymphoblastic leukemia with t(4;11)(q21;q23)/AF4-MLL in a patient with mantle cell lymphoma after recent aggressive chemotherapy: a unique case report. 24817983 2015
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 GeneticVariation disease BEFREE Involvement of the MLL gene in adult T-lymphoblastic leukemia. 22927255 2013
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 AlteredExpression disease BEFREE Here we show that depending on extrinsic cues, human neonatal CD34(+) cells are readily immortalized along either the myeloid or lymphoid lineage upon MLL-AF9 expression and give rise to mainly lymphoid leukemia in immunocompromised mice. 23178754 2013
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 GeneticVariation disease BEFREE Translocations and amplifications of the mixed lineage leukemia-1 (MLL1) gene are associated with aggressive myeloid and lymphocytic leukemias in humans. 22665483 2012
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 Biomarker disease BEFREE MuLV-infected Mll-AF9 mice succumbed to disease significantly faster than controls presenting predominantly with myeloid leukemia while infected WT animals developed predominantly lymphoid leukemia. 22427200 2012
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 Biomarker disease BEFREE The MLL gene is a recurrent target for translocations in both acute myeloid and acute lymphoid leukemias. 20175452 2010
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 Biomarker disease BEFREE MLL1 is well known to be rearranged in myeloid and lymphoid leukemias in children and adults. 20236313 2010
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 GeneticVariation disease BEFREE T-cell lymphoblastic leukemia in early childhood presents NOTCH1 mutations and MLL rearrangements. 19631984 2010
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 Biomarker disease CTD_human Modeling the initiation and progression of human acute leukemia in mice. 17463288 2007
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 GeneticVariation disease LHGDN Topoisomerase II inhibitors are cell cycle-specific DNA-damaging agents which correlate with chromosomal translocations involving the mixed-lineage leukemia/myeloid lymphoid leukemia (MLL) gene on chromosome 11. 16357944 2006
CUI: C0023448
Disease: Lymphoid leukemia
Lymphoid leukemia
0.400 Biomarker disease BEFREE The MLL gene is involved in many chromosomal translocations leading to both acute myeloid and lymphoid leukemia. 12665971 2003