MMP3, matrix metallopeptidase 3, 4314

N. diseases: 473; N. variants: 24
Disease: Disorder of tendon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151936
Disease: Disorder of tendon
Disorder of tendon 		0.030 GeneticVariation group BEFREE Furthermore, the MMP3 gene variant rs679620 and the COL5A1 marker rs12722 interact to modify the risk of tendinopathy. 19042922 2009
CUI: C0151936
Disease: Disorder of tendon
Disorder of tendon 		0.030 AlteredExpression group BEFREE Both receptors did not show significant transcriptional regulation in tendinopathy, although MMP3 was downregulated and MMP9 was upregulated in tendinopathy. 19148938 2009
CUI: C0151936
Disease: Disorder of tendon
Disorder of tendon 		0.030 AlteredExpression group BEFREE Immunoblotting of proteins extracted from the same tendon samples showed that three of four normal tissue samples taken from individuals without apparent tendon disorder had much higher levels of MMP-3 protein than 'normal' or degenerate samples from patients with tendinosis. 11420148 2001