|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Also, BDNF and MMP-9 levels may be affected by metabolic parameters, such as obesity or dyslipidemia.
|
31464540 |
2019 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
According to our results, although serum KIM-1, NGAL, OPN, MMP-9, and urine MMP-9, urine KIM-1 do not appear to be ideal markers to evaluate renal injury in the early period of obesity, the serum levels of cystatin C and urine NGAL, urine OPN can be used as a good marker for assessing the renal effect of obesity which can lead end stage renal disease in pediatric population.
|
30035656 |
2018 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Our study suggests that MMP-9 levels are influenced by obesity and may directly participate in the progressive LV remodelling process, suggesting a possible role for a higher cardiovascular risk in apparent resistant hypertensive subjects.
|
27825280 |
2017 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
All anthropometric, metabolic factors and biomarkers were higher in children with obesity except apolipoprotein (Apo)-AI, cholesterol, high-density lipoprotein cholesterol (HDL-c), and adiponectin, which were lower in the obesity group; and glucose, low-density lipoprotein cholesterol (LDL-c), and matrix metalloproteinase-9 that did not differ between groups.
|
28771179 |
2017 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Matrix metalloproteinase (MMP)-9 is known to degrade the extracellular matrix and increased MMP-9 levels are related with the pathogenesis of many inflammatory conditions including obesity.
|
28419983 |
2017 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We examined whether MMP-9 polymorphisms and haplotypes are associated with obesity, and whether they affect MMP-9 levels in obese subjects.
|
27146834 |
2016 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Obesity with and without T2DM is associated with an increase in the expression of IL-4, LIGHT, MMP-9 and CCR-2; plasma NOM and MMP-9 concentrations are also increased.
|
23804543 |
2014 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Higher plasma and tissue MMP-9 levels are found in obese; therefore, we evaluated if the functional C(-1562)T polymorphism (rs3918242) located in promoter region of the MMP-9 gene is associated with obesity in women.
|
22304569 |
2012 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
CTD_human |
Fate and complex pathogenic effects of dioxins and polychlorinated biphenyls in obese subjects before and after drastic weight loss.
|
21156398 |
2011 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
Furthermore, LCN2 is associated with MMP-2 and MMP-9 activities as well as with pro-inflammatory markers suggesting its potential involvement in the low-grade chronic inflammation accompanying obesity.
|
19466389 |
2009 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
The only association between MMP-9 PM and other risk factors for AMD was with BMI (Spearman's R = 0.298, P < 0.00005): all patients with both microsatellites > or = 22 CA repeats were overweight or obese (chi2 test P < 0.0005, compared to other genotypes).
|
15834245 |
2005 |