MYH9, myosin heavy chain 9, 4627

N. diseases: 196; N. variants: 38
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.340 AlteredExpression disease BEFREE TFPI-2 suppresses breast cancer cell proliferation and invasion through regulation of ERK signaling and interaction with actinin-4 and myosin-9. 30258071 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.340 Biomarker disease CTD_human Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma. 28650484 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.340 AlteredExpression disease BEFREE The expression of these proteins was biochemically validated, and expression of myosin-9 in clinical breast cancer samples was further shown to be altered in primary tumors versus corresponding lymph node metastasis. 22623409 2012
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.340 AlteredExpression disease BEFREE These findings suggest that 25-MHA-mediated inhibitory activity of human breast cancer cell growth might be related with the cell cycle arrest and modulation of signal transduction pathways. 21782877 2011
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.340 Biomarker disease BEFREE Recently, MYH1 and MYH9 have been identified as candidate breast cancer genes in a systematic analysis of the breast cancer genome. 18796164 2008