NFATC2, nuclear factor of activated T cells 2, 4773

N. diseases: 154; N. variants: 22
Disease: Colitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009319
Disease: Colitis
Colitis 		0.030 Biomarker disease BEFREE Here, we used an experimental model of colitis-associated colorectal carcinoma to investigate the contribution of NFATc2 to the promotion of colonic tumors. 22738913 2012
CUI: C0009319
Disease: Colitis
Colitis 		0.030 Biomarker disease BEFREE Severe colitis in LRRK2-deficient mice was associated with enhanced nuclear localization of NFAT1. 21983832 2011
CUI: C0009319
Disease: Colitis
Colitis 		0.030 Biomarker disease LHGDN Collectively, these results define a unique regulatory role for NFATc2 in colitis by controlling mucosal T cell activation in an IL-6-dependent manner. 18710929 2008