NFATC2, nuclear factor of activated T cells 2, 4773

N. diseases: 154; N. variants: 22
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.030 AlteredExpression disease BEFREE We previously demonstrated that the calcium-responsive transcription factor nuclear factor of activated T cells-1 (NFAT1) is activated in glioblastomas and regulates the invasion of tumor cells. 30940662 2019
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.030 AlteredExpression disease BEFREE The results indicated that miR-454-3p executed the tumor suppressive activity via downregulating NFATc2 in GBM. 31181312 2019
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.030 Biomarker disease BEFREE These findings demonstrate that PMA/Io can induce glioblastoma cell death through the NFAT1-Fas/FasL pathway. 24130787 2013