NGF, nerve growth factor, 4803

N. diseases: 616; N. variants: 11
Disease: Amnesia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002622
Disease: Amnesia
Amnesia 		0.310 Therapeutic disease CTD_human Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles. 19694610 2009
CUI: C0002622
Disease: Amnesia
Amnesia 		0.310 Therapeutic disease CTD_human The antiamnesic activity of nerve growth factor (NGF) in various medicinal forms [aqueous NGF solution with and without polysorbate-80 (PS-80) additives, NGF adsorbed on poly(butyl) cyanoacrylate (PBCA) nanoparticles with and without PS-80 coating] has been studied in rats with model amnesia induced by scopolamine (2 mg/kg, s.c.). 16405025 2006
CUI: C0002622
Disease: Amnesia
Amnesia 		0.310 Biomarker disease BEFREE These results show that naturally occurring age-related memory loss can be reversed by grafting cells engineered to secrete NGF directly to the NBM, and that either cholinergic hyper- or hypofunction may lead to cognitive impairments. 7722631 1995