Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.320 Biomarker phenotype BEFREE Since that time, NGF has also been shown to play a key role in the generation of acute and chronic pain and in hyperalgesia in diverse pain states. 23157347 2013
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.320 Biomarker phenotype CTD_human To confirm that the remaining, TrkA(+)/IB4(-), nociceptors are still functional, we evaluated if nerve growth factor (NGF) induced hyperalgesia. 20457222 2011
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.320 Biomarker phenotype CTD_human While pretreatment with IB4-saporin eliminated the acute mechanical hyperalgesia induced by glia-derived neurotrophic factor (GDNF), NGF and PsiepsilonRACK, a highly selective activator of PKCepsilon, induced robust hyperalgesia. 20457222 2011
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.320 Biomarker phenotype CTD_human After injection of NGF, GDNF or PsiepsilonRACK, at a time at which hyperalgesia induced by PGE(2) is markedly prolonged (hyperalgesic priming) in control rats, in IB4-saporin-pretreated rats PGE(2) failed to produce this prolonged hyperalgesia. 20457222 2011
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.320 Biomarker phenotype BEFREE Nerve growth factor evokes hyperalgesia in mice lacking the low-affinity neurotrophin receptor p75. 9835221 1999