NGF, nerve growth factor, 4803

N. diseases: 616; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0442874
Disease: Neuropathy
Neuropathy
0.070 Biomarker group BEFREE Initial efforts attempted to use NGF agonistically for Alzheimer's disease and neuropathies. 31026504 2020
CUI: C0442874
Disease: Neuropathy
Neuropathy
0.070 Biomarker group BEFREE We will review neuropathies and clinical presentations that result from the disruption of NGF signalling in HSAN type IV and HSAN type V and review current advances in developing anti-NGF therapy for the clinical management of pain. 23157347 2013
CUI: C0442874
Disease: Neuropathy
Neuropathy
0.070 GeneticVariation group BEFREE A novel NGF mutation clarifies the molecular mechanism and extends the phenotypic spectrum of the HSAN5 neuropathy. 20978020 2011
CUI: C0442874
Disease: Neuropathy
Neuropathy
0.070 AlteredExpression group BEFREE These results indicate that expression of NGF or NT-3 driven by LAP2 is sufficient to prevent the development of neuropathy 6 months after vector inoculation in rats. 15927533 2005
CUI: C0442874
Disease: Neuropathy
Neuropathy
0.070 AlteredExpression group BEFREE The mRNA levels of nerve growth factor (NGF), glial cell line-derived neurotrophic factor (GDNF), ciliary neurotrophic factor (CNTF), and interleukin-6 (IL-6) were examined in sural nerves of 22 patients with acute necrotizing vasculitic neuropathies. 11360269 2001
CUI: C0442874
Disease: Neuropathy
Neuropathy
0.070 AlteredExpression group BEFREE This study set out to establish a novel procedure for the measurement of human nerve growth factor (NGF) messenger ribonucleic acid (mRNA) and to use this method to measure NGF expression in skin biopsies from control subjects and from patients with early neuropathies. 10229303 1999
CUI: C0442874
Disease: Neuropathy
Neuropathy
0.070 Biomarker group BEFREE To determine whether NGF could influence this neuropathy, 6-month-old control and diabetic mice were divided into the following groups: 1) control + vehicle, 2) diabetic + vehicle, and 3) diabetic + NGF (1 mg/kg, 3x week, s.c.). 9753304 1998