NOS2, nitric oxide synthase 2, 4843

N. diseases: 783; N. variants: 28
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.340 Biomarker disease BEFREE Animal studies have allowed important insights into the role of the nitric oxide synthase (NOS) enzymes in atherosclerosis and hypertension, as well as in stroke. 22153699 2012
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.340 Biomarker disease CTD_human Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas. 20720404 2010
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.340 GeneticVariation disease BEFREE We amplified these (AAAT) repeat variants from the NOS2A gene (denoted iNOS R4 and iNOS R5) from 325 Finnish men included in the Helsinki Sudden Death Study, and studied their association with indices of stenosis and atherosclerosis of the left anterior descending artery (LAD), right coronary artery (RCA) and left circumflex artery (LCX). 14636285 2003
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.340 AlteredExpression disease BEFREE This is supported by the fact that specific inhibition of endogenous iNOS activity with L-N6-(1-iminoethly)-lysine accelerates the progression of vasculopathy in transplantation atherosclerosis. 11168974 2001
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.340 Biomarker disease BEFREE The aim of the present study was to examine the topographical and cellular distribution of inducible nitric oxide synthase (iNOS or NOS II) within different stages of atherosclerosis and its colocalization with ceroid deposits and nitrotyrosine. 10690346 1999