NOS2, nitric oxide synthase 2, 4843

N. diseases: 783; N. variants: 28
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 Biomarker disease BEFREE The variant is also significantly more common among PDD-NOS cases than in AD cases. 22892527 2013
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 Biomarker disease BEFREE If the gut microbiota differences among AD and PDD-NOS and HC children are one of the concomitant causes or the consequence of autism, they may have implications regarding specific diagnostic test, and/or for treatment and prevention. 24130822 2013
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 Biomarker disease CTD_human Family-based association study between NOS-I and -IIA polymorphisms and autism spectrum disorders in Korean trios. 18563708 2009
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 Biomarker disease BEFREE Approximately three-fourths of the children with SLOS (71-86% depending on the evaluation method) had an ASD, about 50% diagnosed with Autistic Disorder and the rest with PDD NOS. 16761297 2006
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 Biomarker disease BEFREE The likelihood of uncovering an etiologically relevant condition in children diagnosed with either PDD-NOS or autistic disorder may be equivalent. 12757358 2003
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 Biomarker disease BEFREE Given the relatively high yield of genetic diagnoses in this population, we believe that children with PDD-NOS or AD should have a detailed evaluation by a clinical geneticist or pediatrician trained in dysmorphology. 9809261 1998