NOS2, nitric oxide synthase 2, 4843

N. diseases: 783; N. variants: 28
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085580
Disease: Essential Hypertension
Essential Hypertension
0.330 Biomarker disease BEFREE Moreover, further investigation of this chromosome, utilizing a polymorphism within the promoter of the iNOS candidate gene, NOS2A, revealed both increased allele sharing among sibpairs (SPLINK: P=0.02; ASPEX: P=0.00004) and positive association (P=0.034) of NOS2A to essential hypertension. 11702222 2001
CUI: C0085580
Disease: Essential Hypertension
Essential Hypertension
0.330 GeneticVariation disease BEFREE A locus for essential hypertension has been found recently on chromosome 17 in the general vicinity of the inducible nitric oxide synthase (iNOS) gene (NOS2A at 17cen-q11.2). 10205225 1999
CUI: C0085580
Disease: Essential Hypertension
Essential Hypertension
0.330 GeneticVariation disease BEFREE The nitric oxide synthase (NOS) gene is thought to be associated with essential hypertension (EH), because NO is implicated in endothelium-mediated vasodilation. 9084930 1997
CUI: C0085580
Disease: Essential Hypertension
Essential Hypertension
0.330 Biomarker disease CTD_human