NOS3, nitric oxide synthase 3, 4846

N. diseases: 706; N. variants: 39
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia
0.530 AlteredExpression disease BEFREE Atorvastatin promotes eNOS expression and is more efficient than ER or exercise in the control of hyperlipidemia and inflammation. 29686722 2018
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia
0.530 GeneticVariation disease BEFREE In conclusion, we have described for the first time a significant correlation of statin treatment and CYP3A4 2 and eNOS gene polymorphisms in T2D, suggesting a new genetic susceptibility factor for insulin resistance and hyperlipidemia in T2D. 24996290 2014
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia
0.530 Biomarker disease RGD Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity. 17895290 2007
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia
0.530 Biomarker disease BEFREE Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells. 12692005 2003
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia
0.530 Biomarker disease CTD_human To study the role of eNOS in the control of the metabolic action of insulin, we assessed insulin sensitivity in conscious mice with disruption of the gene encoding for eNOS. eNOS(-/-) mice were hypertensive and had fasting hyperinsulinemia, hyperlipidemia, and a 40% lower insulin-stimulated glucose uptake than control mice. 11457755 2001