NPPB, natriuretic peptide B, 4879

N. diseases: 193; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.370 Biomarker disease BEFREE Increasing BNP among participants from 1990-1992 to 1996-1998 was associated with increased AF risk. 31564186 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.370 Biomarker disease BEFREE NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure. 30912456 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.370 Biomarker disease BEFREE Three simple clinical risk factors (age, sex, and BMI) and two biomarkers (elevated BNP and elevated FGF-23) identify patients with AF. 30615112 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.370 Biomarker disease BEFREE We sought to explore the associations between the presence of AF and circulating biomarkers reflecting cardiovascular function (N-terminal pro-brain natriuretic peptide, NT-pro BNP), endothelial function (big endothelin-1, big ET-1), inflammation (high-sensitivity C-reactive protein), and myocardial damage (cardiac troponin I, cTnI) in HCM patients with and without left ventricular outflow tract obstruction (LVOTO).In all, 375 consecutive HCM in-hospital patients were divided into an AF group (n = 90) and a sinus rhythm (SR) group (n = 285) according to their medical history and electrocardiogram results.In comparison with the SR group, peripheral concentrations of big ET-1, NT-pro BNP, and cTnI were significantly higher in patients with AF. 30626765 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.370 AlteredExpression disease BEFREE Here, patients with AF showed a significant increase in expression levels and activity of HDAC3, phosphorylated HDAC5 and fetal genes (β-MHC, BNP) in atrial tissue compared to controls in sinus rhythm. 30321539 2018
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.370 AlteredExpression disease LHGDN Determinants of brain natriuretic peptide levels in patients with lone atrial fibrillation. 16377932 2006
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.370 Biomarker disease CTD_human Valsartan reduces the incidence of atrial fibrillation in patients with heart failure: results from the Valsartan Heart Failure Trial (Val-HeFT). 15864246 2005
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.370 AlteredExpression disease BEFREE Persistent AF was associated with higher mRNA expression of pro-BNP (+66%, P = 0.04, in patients without valvular disease, and +69%, P < 0.01, in patients with valvular disease) and lower mRNA expression of NPR-A (-58%, P = 0.02, in patients without valvular disease, and -62 %, P < 0.01, in patients with valvular disease). 10376920 1999