OAS1, 2'-5'-oligoadenylate synthetase 1, 4938

N. diseases: 72; N. variants: 11
Disease: Prostate carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.020 GeneticVariation disease BEFREE Two sub-pathways (intracellular antiviral molecules and extracellular pattern recognition) and four genes in these sub-pathways (TLR1, TLR6, OAS1, and OAS2) were nominally associated with advanced prostate cancer risk and harbor several SNPs nominally associated with advanced prostate cancer risk. 23272139 2012
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.020 GeneticVariation disease BEFREE In this study, the authors investigated the association of this functional OAS1 polymorphism (rs2660) with prostate cancer. 21638280 2011