Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1096184
Disease: West Nile viral infection
West Nile viral infection
0.040 Biomarker disease BEFREE The OAS1 gene, previously associated with WNV-induced clinical disease, was not associated with the presence of anti-WNV antibodies. 31175514 2019
CUI: C1096184
Disease: West Nile viral infection
West Nile viral infection
0.040 GeneticVariation disease BEFREE In particular we found variation within the OAS1 (meta-OR = 0.83, 95% CI: 0.69-1.00) and CCR5 (meta-OR = 1.29, 95% CI: 1.08-1.53) genes is significantly associated with West Nile virus disease, while variation within MICB (meta-OR = 2.35, 95% CI: 1.68-3.29), PLCE1 (meta-OR = 0.55, 95% CI: 0.42-0.71), MBL2 (meta-OR = 1.54, 95% CI: 1.02-2.31), and IFN-γ (meta-OR = 2.48, 95% CI: 1.30-4.71), is associated with dengue disease. 29929468 2018
CUI: C1096184
Disease: West Nile viral infection
West Nile viral infection
0.040 GeneticVariation disease BEFREE Together, these data identify OAS1 SNP rs10774671 as a host genetic risk factor for initial infection with WNV in humans. 19247438 2009
CUI: C1096184
Disease: West Nile viral infection
West Nile viral infection
0.040 Biomarker disease BEFREE Although still preliminary, a few recent observations also substantiate a possible role for OAS1 in human susceptibility to viral infections (West Nile virus, SARS, etc.) and its possible involvement in some other diseases such as type 1 diabetes and multiple sclerosis. 18727488 2008